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Painkillers For ToothachePosted on April 13, 2010. What are really good painkillers for toothache? ambesol, clove oil and cloves in the mouth or a tablet crusk benedryl and use the powder as a rub around the tooth, it numbs the surface The dentist I work for still prescribed Motrin or amoxicillin. She says they are the best painkiller for toothache. CommentsThere are no comments.Leave a Comment | Popular My Friends |