Posted on February 28, 2010.
Bladder dissolving agents Oral Drugs Drug Type
Bladder dissolving agent.
How the drug works
Helps dissolve cholesterol gallstones Ursodiol. It is more effective if the calculations are small or "floating". Patients must have a vesicle work.
Uses
To dissolve cholesterol gallstones less than 20 mm in diameter in patients who are not good candidates for surgery because of systemic disease, advanced age, or reaction to general anesthesia.
For prevention of gallstones in obese patients a rapid weight loss.
Bladder recurrence: Treatment requires months of treatment. complete dissolution does not always occur and recurrence within 5 years was observed in 50% or less of patients. Consider alternative therapy if possible.
Pregnancy: There are no adequate and well controlled studies in pregnant women. Use only when absolutely necessary and the potential benefits outweigh the potential risks to the fetus.
Lactation: It is not known if ursodiol appears in breast milk. Consult your doctor before you begin breastfeeding.
Children: The safety and efficacy have not been established.
Laboratory tests will be needed during treatment. The tests include liver function analysis.
Drug Interactions
Tell your doctor or pharmacist if you are taking or plan to take over the counter or prescription medications or dietary supplements with this drug. doses of medication may be necessary to change or a different drug prescribed. The following drugs and drug classes interact with this medicine.
Antacids containing aluminum (aluminum hydroxide, for example)
Clofibrate (eg, Atromid-S)
Contraceptives, oral (eg, Ortho-Novum)
Bile acid sequestrants (eg cholestyramine)
eg estrogen (, ethinyl estradiol)
Adverse
Every drug can produce side effects. Many patients experience no, or minor side effects. The frequency and severity of side effects depend on many factors including dose, duration of treatment and individual sensitivity. Possible side effects include.
Digestive: nausea, vomiting, diarrhea, abdominal pain (especially in the upper right side); indigestion, constipation, gas, inflammation of the gallbladder inflammation of the mouth.
Nervous system: headache, fatigue, anxiety, depression, sleep disorders.
Skin: rash, itching, hives, dry skin, sweating, thin hair.
Other sores in the mouth metallic taste, muscle and joint pain, cough, runny nose, sore backs.
Guidelines for Use
Use exactly as prescribed. Otherwise, the gallstones may dissolve very slowly or not at all.
If a dose is missed, take it as soon as possible. If several hours have passed or if it is almost time for your next dose, do not double the dose to catch up (unless to do so by your doctor). If more than one dose is missed or it is necessary to establish a new dosing regimen, please contact your doctor or pharmacist.
Carefully follow the diet prescribed by your doctor.
Contact your doctor if diarrhea, stomach pain, sudden pain in the upper right side, nausea or vomiting.
Therapy takes months. Complete dissolution of gallstones does not occur in all patients, and recurrence within 5 years occurs in up to 50% of patients.
The long-term (over 24 months) of this drug are not known.
Laboratory tests will be required to monitor therapy. Make sure your appointment.
Store below 86 ° F.